ISR4221/K9 is the base Cisco ISR 4221 order described with two Gigabit Ethernet interfaces, two NIM slots, 8 GB flash, 4 GB DRAM and IP Base. The exact order differs from ISR4221X/K9, whose ordering row lists 8 GB DRAM, and from separately named security bundles. Preserve the complete PID when comparing quotations.
Cisco states that ISR4221/K9 does not support UC voice. Its documented base performance level is 35 Mbps, with FL-4220-PERF-K9 listed separately to raise that level to 75 Mbps. Do not infer voice capability or the higher licensed performance from the presence of module slots or the ISR 4000 family name.
Cisco identifies IOS XE 17.9.x and 17.12.x as the final supported trains for the affected ISR 4000 platforms, while 17.10.x and 17.11.x are excluded. The last support date is November 30, 2028, subject to applicable entitlement. Verify the actual installed release and license state before matching this router to an existing deployment.
The exact ISR4221/K9 migration row points to C8200L-1N-4T. Use that as a starting point for an interface and service comparison. It does not prove an existing module, software right or saved configuration transfers unchanged to the replacement platform.
| Item | Official fact and boundary |
|---|---|
| Exact order | ISR4221/K9 |
| Base interface/slots | 2 GE; 2 NIM |
| Ordering-row memory | 8 GB flash; 4 GB DRAM |
| Base license identity | IP Base |
| UC voice | Not supported |
| Performance | 35 Mbps base; 75 Mbps with separate PERF license |
| Cisco migration row | C8200L-1N-4T |
Product Quotation | ![]() | Condition and Packaging | |
![]() | Technical Support Enquiry | Returns and Replacement | |
Shipping Arrangements | ![]() | Warranty Terms |
ISR4221/K9 USED Cisco ISR 4221 Router is a CISCO Router ISR 4000 product supplied by YYST Global for enterprise IT procurement and infrastructure projects.
For ISR4221/K9, the manufacturer specification lists base interface/slots as 2 GE; 2 NIM.
For ISR4221/K9, the manufacturer specification lists ordering-row memory as 8 GB flash; 4 GB DRAM.
Contact YYST Global to confirm availability for ISR4221/K9, the required quantity, exact configuration, delivery destination and current lead time before ordering. A product listing does not confirm current inventory.
The current reference price for ISR4221/K9 is US$ 675.00. Final pricing can change based on stock, quantity, configuration and delivery destination.
Related products

Cisco ISR4221-SEC/K9 is the ISR 4221 router bundle with a SEC license. The platform provides two onboard Gigabit Ethernet interfaces and two NIM slots; its separate performance license raises the published aggregate tier from 35 to 75 Mbps.

ISR4221X/K9 is the 8GB-DRAM version of the Cisco 4221 branch router, with two onboard Gigabit Ethernet interfaces and two NIM slots. Cisco ended sale in November 2023; final support is November 30, 2028, subject to entitlement.

ISR4221-AX/K9 is the Cisco ISR 4221 Application Experience bundle with APP and SEC licenses. Confirm exact chassis inventory, bundle entitlement, software eligibility and lifecycle support before purchase.

ISR4461/K9 is Cisco's base ISR 4461 router with two 10-Gigabit and four Gigabit onboard interfaces, three NIM slots and three service-module slots. Its 1.5 Gbps default aggregate forwarding tier is distinct from the separately licensed 3 Gbps tier. Cisco ended sale January 20, 2025; final support is January 31, 2030 under applicable entitlement terms.

ISR4431/K9 is the Cisco ISR 4431 base router order with four onboard Gigabit Ethernet interfaces, three NIM slots and one ISC slot. Cisco ended sale on November 7, 2023; general software maintenance ended August 31, 2025. Support eligibility and installed performance licenses require verification before procurement. The manufacturer family image is representative, not a photograph of a supplied unit.

ISR4431-DNA is the Cisco ISR 4431 router order with a DNA subscription, four Gigabit interfaces and three NIM slots. Verify the quoted software tier and term; hardware support ends November 30, 2028.

ISR4351-SEC/K9 is the Cisco ISR 4351 security bundle identified in the official ordering row as including the SEC license. See the verified interface, replacement and lifecycle boundaries before requesting a quote.

ISR4451-X-SEC/K9 is a Cisco security-bundle router with four Gigabit Ethernet interfaces and 1 Gbps default aggregate throughput. The 2 Gbps performance license is separate; review final IOS XE train and support limits before retaining this legacy platform.